Effect of allylic and homoallylic substituents on cross metathesis: syntheses of prostaglandins F2a and J2

Sheddan, Neil A.; Arion, Vladimir B.; Mulzer, Johann.   

Tetrahedron Letters  (2006),  47(37),  6689-6693. 

We describe the effect of allylic (C15) and homoallylic (C11) substituents on cross metathesis reactions with Corey lactone derivatives. This strategy has led to the successful syntheses of PGF2α and PGJ2.