Total synthesis and configurational assignment of pasteurestin A and B
Koegl, Marion; Brecker, Lothar; Warrass, Ralf; Mulzer, Johann.
Angewandte Chemie, International Edition (2007), 46(48), 9320-9322.
Fresh pasture for the [2+2+2] cycloaddition: The two sesquiterpenoids pasteurestin A and B, which exhibit strong and selective antibacterial activity against Pasteurella haemolytica, have been prepared in a synthesis relying on a [2+2+2] Vollhardt enediyne cycloaddition. The previously unknown absolute and relative configurations were established, and the biological profile was specified more precisely.
Inside cover: total synthesis and configurational assignment of pasteurestin a and B (Angew. Chem. Int. Ed. 48/2007).
Kogl Marion; Brecker Lothar; Warrass Ralf; Mulzer Johann
Angewandte Chemie (International ed. in English) (2007), 46(48), 9120.
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