Logo der Universität Wien

Total synthesis and configurational assignment of pasteurestin A and B

Koegl, Marion; Brecker, Lothar; Warrass, Ralf; Mulzer, Johann.

Angewandte Chemie, International Edition  (2007),  46(48),  9320-9322.

Fresh pasture for the [2+2+2] cycloaddition: The two sesquiterpenoids pasteurestin A and B, which exhibit strong and selective antibacterial activity against Pasteurella haemolytica, have been prepared in a synthesis relying on a [2+2+2] Vollhardt enediyne cycloaddition. The previously unknown absolute and relative configurations were established, and the biological profile was specified more precisely.


Inside cover: total synthesis and configurational assignment of pasteurestin a and B (Angew. Chem. Int. Ed. 48/2007).

Kogl Marion; Brecker Lothar; Warrass Ralf; Mulzer Johann 

Angewandte Chemie (International ed. in English)  (2007),  46(48),  9120.




Johann Mulzer
Institute for Organic Chemistry
University of Vienna

Währingerstraße 38
A-1090 Vienna

University of Vienna | Universitätsring 1 | 1010 Vienna | T +43-1-4277-0