Protecting-group-free formal synthesis of platensimycin

Tiefenbacher, Konrad; Mulzer, Johann

Angewandte Chemie, International Edition  (2007),  46(42),  8074-8075.

Short cut: In a new approach to the recently discovered antibiotic platensimycin (1), Nicolaou's late key intermediate is synthesised without the use of protecting groups in five steps from a readily available starting material.