An expeditious asymmetric formal synthesis of the antibiotic platensimycin

Tiefenbacher, Konrad; Troendlin, Lars; Mulzer, Johann; Pfaltz, Andreas

Tetrahedron (2010), 66, (33), 6508-6513.

A short enantioselective and protecting group free access to the novel antibiotic platensimycin is reported. The crucial stereogenic information is provided by iridium catalyzed asymmetric hydrogenation.