Application of the Rodriguez-Pattenden Photo-Ring Contraction: Total Synthesis and Configurational Reassignment of 11-Gorgiacerol and 11-Epigorgiacerol
Weinstabl, Harald; Gaich, Tanja; Mulzer, Johann
Org. Lett. 2012, 14(11), 2834-2837.
A stereospecific photochemical ring contraction was used as the key step in the first total synthesis of the marine pseudopteranyl diterpene 11-gorgiacerol and its 11-epimer. The synthesis allowed the correction of the configurations that had been misassigned in the literature. In addition, some novel pseudopteranyl derivatives have been made.
Johann Mulzer
Institute for Organic Chemistry
University of Vienna
Währingerstraße 38
A-1090 Vienna
Institute for Organic Chemistry
University of Vienna
Währingerstraße 38
A-1090 Vienna