Selected Diastereoselective Reactions: Substrate Controlled Stereoselective Conjugate Addition Reactions with Organocopper Reagents

Siengalewicz, Peter; Mulzer, Johann; Rinner, Uwe

Comprehensive Chirality 2012, 2, 441-471.

The importance of conjugate addition reactions with organocopper reagents has increased since the seminal synthetic application, as reported by Robinson in the early 1940s. This review chapter is intended to provide an overview of substrate-controlled diastereoselective conjugate organocuprate addition reactions, utilized in the preparation of complex natural products on selected syntheses which have been published within the past decade.